A Case of Clomipramine-Induced Chronic Dilated Cardiomyopathy
Korean Circulation Journal
;
: 1393-1397, 1998.
Article
in Korean
| WPRIM
| ID: wpr-112458
ABSTRACT
Dilated cardiomyopathy is a primary myocardial disease characterized by ventricular dilatation and impaired ventricular contractility. The etiology of dilated cardiomyopathy has not been known yet, but toxin such as alcohol, thiamine deficiency, endocrine disorder, viral or bacterial infection, hereditary disorder, and muscular dystrophy may be related to dilated cardiomyopathy. Cocaine abuse and anticancer drugs (especially doxorubicin) were reported as the causes of drugs of dilated cardiomyopathy also. Recently we experinced a case of dilated cardiomyopathy in 30 years old man who developed dilated cardiomyopathy on chronic clomipramine (one of trcyclic antidepressant drugs) treatment for a obsessive-compulsive disorder. He became asymptomatic and normalization of left ventricular diameters and function was evidenced echocardiographically after withdrawal of the drug. The possible association of cardiomyopathy and tricyclic antidepressant drugs and possibility of functional improvement after tricyclic antidepressant drugs withdrawal should be kept in mind.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thiamine Deficiency
/
Bacterial Infections
/
Cardiomyopathy, Dilated
/
Clomipramine
/
Cocaine-Related Disorders
/
Dilatation
/
Antidepressive Agents, Tricyclic
/
Cardiomyopathies
/
Obsessive-Compulsive Disorder
Limits:
Adult
/
Humans
Language:
Korean
Journal:
Korean Circulation Journal
Year:
1998
Type:
Article
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