Review of Biological Network Data and Its Applications
Genomics & Informatics
;
: 200-210, 2013.
Article
in English
| WPRIM
| ID: wpr-11254
ABSTRACT
Studying biological networks, such as protein-protein interactions, is key to understanding complex biological activities. Various types of large-scale biological datasets have been collected and analyzed with high-throughput technologies, including DNA microarray, next-generation sequencing, and the two-hybrid screening system, for this purpose. In this review, we focus on network-based approaches that help in understanding biological systems and identifying biological functions. Accordingly, this paper covers two major topics in network biology reconstruction of gene regulatory networks and network-based applications, including protein function prediction, disease gene prioritization, and network-based genome-wide association study.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Biology
/
Mass Screening
/
Oligonucleotide Array Sequence Analysis
/
Gene Regulatory Networks
/
Genome-Wide Association Study
/
Dataset
Type of study:
Screening study
Language:
English
Journal:
Genomics & Informatics
Year:
2013
Type:
Article
Similar
MEDLINE
...
LILACS
LIS