Myasthenia in Acquired Neuromyotonia
Journal of Clinical Neurology
;
: 69-71, 2014.
Article
in English
| WPRIM
| ID: wpr-113288
ABSTRACT
BACKGROUND:
Acquired neuromyotonia (NMT) forms part of the spectrum of acquired peripheral nerve hyperexcitability syndrome, and is thought to be caused by antibodies to voltage-gated potassium channels (VGKC). Exertional weakness is unusual unless autoimmune myasthenia gravis (MG) is superimposed. CASE REPORT A case of acquired NMT accompanied by exertional weakness without coexistence of seropositive MG is reported herein.CONCLUSIONS:
Clinical and electrophysiological observations suggest that the cholinergic overactivity in NMT can compromise the safety factor sufficiently to cause a defect in neuromuscular junction transmission.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Peripheral Nerves
/
Isaacs Syndrome
/
Potassium Channels, Voltage-Gated
/
Antibodies
/
Myasthenia Gravis
/
Neuromuscular Junction
Language:
English
Journal:
Journal of Clinical Neurology
Year:
2014
Type:
Article
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