Clinical evaluation of a biphasic calcium phosphate grafting material in the treatment of human periodontal intrabony defects
Journal of Periodontal & Implant Science
;
: 127-135, 2012.
Article
in English
| WPRIM
| ID: wpr-11334
ABSTRACT
PURPOSE:
The aim of this study was to compare the clinical outcome of open flap debridement (OFD) with a biphasic calcium phosphate (BCP) graft to that of OFD without BCP graft for the treatment of intrabony periodontal defects (IBDs).METHODS:
The study included 25 subjects that had at least one intrabony defect of 2- or 3-wall morphology and an intrabony component> or =4 mm as detected radiographically. Subjects were randomly assigned to treatment with (BCP group, n=14) or without BCP (OFD group, n=11). Clinical parameters were recorded at baseline and 6 months after surgery and included the plaque index, gingival index, probing depth (PD), clinical attachment level (CAL), and gingival recession (REC). A stringent plaque control regimen was enforced for all of the patients during the 6-month observation period.RESULTS:
In all of the treatment groups, significant PD reductions and CAL gains occurred during the study period (P<0.01). At 6 months, patients in the BCP group exhibited a mean PD reduction of 3.7+/-1.2 mm and a mean CAL gain of 3.0+/-1.1 mm compared to the baseline. Corresponding values for the patients treated with OFD were 2.5+/-0.8 mm and 1.4+/-1.0 mm, respectively. Compared to OFD group, the additional CAL gain was significantly greater in the patients in BCP group (P=0.028). The additional PD reduction was significant for the BCP group (P=0.048). The REC showed a significant increase in both groups, and the amount of recession was significantly smaller in the BCP group than OFD group (P=0.023). In radiographic evaluation, the height of the bone fill in the BCP group was significantly greater than OFD group.CONCLUSIONS:
The clinical benefits of BCP found in this study indicate that BCP may be an appropriate alternative to conventional graft materials.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Calcium Phosphates
/
Periodontal Index
/
Calcium
/
Alveolar Bone Loss
/
Bone Transplantation
/
Debridement
/
Chronic Periodontitis
/
Gingival Recession
/
Hydroxyapatites
Limits:
Humans
Language:
English
Journal:
Journal of Periodontal & Implant Science
Year:
2012
Type:
Article
Similar
MEDLINE
...
LILACS
LIS