Value of the immunology in the classification of the types of leukemia that it is difficult to diagnose

ABSTRACT

From 1996 to 2000, 609 patients of acute leukemia in NIHBT, Bach Mai hospital were applied immunophenotype. The results as follow Acute myeloid leukemia (AML) 408 patients (67%) including AML (CD14-) 367patients (60.3%), AML (CD14+) 41patients (6.7%). Acute lymphoid leukemia (ALL) 123 patients (20.2%) including PreT 16 patients (2.6%), T 3 patients (0.5%), Early B 2 patients (0.3), PreB 81 patients (13.3%), 21 patients (3.45%), 78 patients (only CD34+). NK acute leukemia 1 patient (CD16/56+), Acute “null-cell” leukemia 17 (all CDs negative on blasts), Mixed acute leute leukemia myoloid-B 16 patients (CD13+, CD33+ and /or CD3; CD7+), Mixed acute leukemia myeloid-NK 7 patients (CD13+, CD33+ and/or CD16/56+). These results contributed effectively to pathological study, folow up treatment and prognosis of acute leukemia