Is Stem Cell-Based Therapy Going on or Out for Cardiac Disease?
Korean Circulation Journal
;
: 87-92, 2009.
Article
in English
| WPRIM
| ID: wpr-113703
ABSTRACT
Acute myocardial infarction and subsequent heart failure are leading causes of death worldwide. Stem cell-based therapies have improved cardiac function in recent clinical trials, but cardiomyocyte regeneration has not been demonstrated in human hearts. Angiogenesis and restoration of cardiac perfusion have been successfully performed using bone marrow derived stem cells and other adult stem cells. Resident cardiac stem cells are known to differentiate into multiple heart cell types, including cardiomyocytes. Furthermore, induced pluripotent stem cells are a focus of research due to the great potential for customized stem cell therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Perfusion
/
Regeneration
/
Stem Cells
/
Bone Marrow
/
Cell Differentiation
/
Cause of Death
/
Myocytes, Cardiac
/
Adult Stem Cells
/
Induced Pluripotent Stem Cells
/
Heart
Limits:
Humans
Language:
English
Journal:
Korean Circulation Journal
Year:
2009
Type:
Article
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