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Predictors of Relapse in Patients with Organizing Pneumonia / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases ; : 190-195, 2015.
Article in English | WPRIM | ID: wpr-114250
ABSTRACT

BACKGROUND:

Although organizing pneumonia (OP) responds well to corticosteroid therapy, relapse is common during dose reduction or follow-up. Predictors of relapse in OP patients remain to be established. The aim of the present study was to identify factors related to relapse in OP patients.

METHODS:

This study was retrospectively performed in a tertiary referral center. Of 66 OP patients who were improved with or without treatment, 20 (30%) experienced relapse. The clinical and radiologic parameters in the relapse patient group (n=20) were compared to that in the non-relapse group (n=46).

RESULTS:

Multivariate analysis demonstrated that percent predicted forced vital capacity (FVC), PaO2/FiO2, and serum protein level were significant predictors of relapse in OP patients (odds ratio [OR], 0.82; 95% confidence interval [CI], 0.70-0.97; p=0.018; OR, 1.02; 95% CI, 1.00-1.04; p=0.042; and OR, 0.06; 95% CI, 0.01-0.87; p=0.039, respectively).

CONCLUSION:

This study shows that FVC, PaO2/FiO2 and serum protein level at presentation can significantly predict relapse in OP patients.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Pneumonia / Recurrence / Vital Capacity / Multivariate Analysis / Retrospective Studies / Follow-Up Studies / Cryptogenic Organizing Pneumonia / Tertiary Care Centers / Methods Type of study: Observational study / Prognostic study / Risk factors Limits: Humans Language: English Journal: Tuberculosis and Respiratory Diseases Year: 2015 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pneumonia / Recurrence / Vital Capacity / Multivariate Analysis / Retrospective Studies / Follow-Up Studies / Cryptogenic Organizing Pneumonia / Tertiary Care Centers / Methods Type of study: Observational study / Prognostic study / Risk factors Limits: Humans Language: English Journal: Tuberculosis and Respiratory Diseases Year: 2015 Type: Article