Predictors of Relapse in Patients with Organizing Pneumonia / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
;
: 190-195, 2015.
Article
in English
| WPRIM
| ID: wpr-114250
ABSTRACT
BACKGROUND:
Although organizing pneumonia (OP) responds well to corticosteroid therapy, relapse is common during dose reduction or follow-up. Predictors of relapse in OP patients remain to be established. The aim of the present study was to identify factors related to relapse in OP patients.METHODS:
This study was retrospectively performed in a tertiary referral center. Of 66 OP patients who were improved with or without treatment, 20 (30%) experienced relapse. The clinical and radiologic parameters in the relapse patient group (n=20) were compared to that in the non-relapse group (n=46).RESULTS:
Multivariate analysis demonstrated that percent predicted forced vital capacity (FVC), PaO2/FiO2, and serum protein level were significant predictors of relapse in OP patients (odds ratio [OR], 0.82; 95% confidence interval [CI], 0.70-0.97; p=0.018; OR, 1.02; 95% CI, 1.00-1.04; p=0.042; and OR, 0.06; 95% CI, 0.01-0.87; p=0.039, respectively).CONCLUSION:
This study shows that FVC, PaO2/FiO2 and serum protein level at presentation can significantly predict relapse in OP patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pneumonia
/
Recurrence
/
Vital Capacity
/
Multivariate Analysis
/
Retrospective Studies
/
Follow-Up Studies
/
Cryptogenic Organizing Pneumonia
/
Tertiary Care Centers
/
Methods
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
Tuberculosis and Respiratory Diseases
Year:
2015
Type:
Article
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