Iodinated contrast media-induced fixed drug eruption
Allergy, Asthma & Respiratory Disease
;
: 375-379, 2015.
Article
in Korean
| WPRIM
| ID: wpr-114307
ABSTRACT
Iodinated contrast media (ICM) can cause not only immediate onset hypersensitivity but also delayed onset hypersensitivity. While the most common form of delayed onset hypersensitivity reaction to ICM is exanthematous eruption, fixed drug eruption (FDE) can occur rarely related to ICM. A 70-year-old male with liver cirrhosis and hepatocellular carcinoma repeatedly experienced erythematous patches on his right forearm and hand 6 hours after exposure to iopromide for computed tomography scan. ICM induced FDE was diagnosed clinically. Intradermal test with 6 kinds of ICM (iobitridol, iohexol, iomeprol, iopamidol, iopromide, and iodixanol) was performed and showed the weakest positive reaction to iohexol compared to the others in 48 hours. After changing iopromide to iohexol based on these results, FDE did not recur. We report here a case of iopromide induced FDE which was successfully prevented by changing ICM to iohexol based on intradermal test results.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Iohexol
/
Iopamidol
/
Intradermal Tests
/
Drug Eruptions
/
Carcinoma, Hepatocellular
/
Contrast Media
/
Forearm
/
Hand
/
Hypersensitivity
/
Hypersensitivity, Delayed
Limits:
Aged
/
Humans
/
Male
Language:
Korean
Journal:
Allergy, Asthma & Respiratory Disease
Year:
2015
Type:
Article
Similar
MEDLINE
...
LILACS
LIS