Impact of Early Enteral Nutrition on In-Hospital Mortality in Patients with Hypertensive Intracerebral Hemorrhage
Journal of Korean Neurosurgical Society
;
: 99-104, 2010.
Article
in English
| WPRIM
| ID: wpr-114778
ABSTRACT
OBJECTIVE:
We conducted this study to evaluate the clinical impact of early enteral nutrition (EN) on in-hospital mortality and outcome in patients with critical hypertensive intracerebral hemorrhage (ICH).METHODS:
We retrospectively analyzed 123 ICH patients with Glasgow Coma Scale (GCS) score of 3-12. We divided the subjects into two groups early EN group ( or = 48 hours, n = 34). Body weight, total intake and output, serum albumin, C-reactive protein, infectious complications, morbidity at discharge and in-hospital mortality were compared with statistical analysis.RESULTS:
The incidence of nosocomial pneumonia and length of intensive care unit stay were significantly lower in the early EN group than in the delayed EN group (p < 0.05). In-hospital mortality was less in the early EN group than in the delayed EN group (10.1% vs. 35.3%, respectively; p = 0.001). By multivariate analysis, early EN [odds ratio (OR) 0.229, 95% CI 0.066-0.793], nosocomial pneumonia (OR = 5.381, 95% CI 1.621-17.865) and initial GCS score (OR = 1.482 95% CI 1.160-1.893) were independent predictors of in-hospital mortality in patients with critical hypertensive ICH.CONCLUSION:
These findings indicate that early EN is an important predictor of outcome in patients with critical hypertensive ICH.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pneumonia
/
Body Weight
/
C-Reactive Protein
/
Serum Albumin
/
Glasgow Coma Scale
/
Cerebral Hemorrhage
/
Incidence
/
Multivariate Analysis
/
Retrospective Studies
/
Hospital Mortality
Type of study:
Incidence study
/
Observational study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Journal of Korean Neurosurgical Society
Year:
2010
Type:
Article
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