Herpes Simplex Virus 2 Infection Rate and Necessity of Screening during Pregnancy: A Clinical and Seroepidemiologic Study
Yonsei Medical Journal
;
: 401-407, 2012.
Article
in English
| WPRIM
| ID: wpr-114999
ABSTRACT
PURPOSE:
This study determined the seroprevalence of herpes virus 2 in gravidas and the differences between herpes virus 2-infected and healthy gravidas. The need to screen gravidas for herpes virus 2 was also evaluated. MATERIALS ANDMETHODS:
A retrospective analysis involving 500 gravidas who underwent herpes virus 2 serologic testing and delivery in our hospital between January 2009 and August 2010 was performed. All patients in the study group were classified as herpes simplex virus 2 (HSV2) positive, and all cases were analyzed with respect to the clinical course of the pregnancy, pregnancy outcome, obstetric complications, and neonatal outcomes. SPSS software (version 14.0) was used for statistical analysis. A chi-square test and Student's t-test were used for statistical analysis.RESULTS:
In the current study, the herpes virus 2 seroprevalence rate in gravidas was 17%. There was no significant difference in the rates of preterm delivery, premature rupture of membranes, preterm labor, and intrauterine growth restriction between the herpes virus 2-infected gravidas and the healthy control group. The rates of spontaneous abortion and sexually transmitted disease were higher in the herpes virus 2 infection group than the healthy control group.CONCLUSION:
After educating gravidas on genital herpes and, if gravidas thereafter consent to herpes virus 2 screening, the risk of neonatal herpes virus 2 infections can be reduced. In addition, examination of gravidas for sexually transmitted diseases would increase as would appropriate treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pregnancy Complications, Infectious
/
Herpes Genitalis
/
Retrospective Studies
/
Herpesvirus 2, Human
/
Herpes Simplex
Type of study:
Diagnostic study
/
Observational study
/
Screening study
Limits:
Adult
/
Female
/
Humans
/
Pregnancy
Language:
English
Journal:
Yonsei Medical Journal
Year:
2012
Type:
Article
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