Successful Response of Oral Etoposide for Refractory Neuroblastoma / 대한소아혈액종양학회지
Korean Journal of Pediatric Hematology-Oncology
;
: 115-120, 2003.
Article
in Korean
| WPRIM
| ID: wpr-115283
ABSTRACT
Intensive chemotherapy with or without stem cell rescue has become widely accepted for treatment of neuroblastoma because increased dose-intensity correlates with improved response rates. For neuroblastoma that is resistant to intensive chemotherapy, further use of high-dose therapy is unlikely to be beneficial. For disease that recurs after myeloablative consolidation, high-dose salvage therapy may not be feasible because of poor bone marrow reserve and may not be justified in view of its morbidity in the absence of a realistic chance for cure. One treatment option in these difficult clinical settings is chronic oral administration of low-dose etoposide. However, there has been a few clinical reports for the experience of oral etoposide for refractory neuroblastoma. We now present 2 cases of successful response of oral etoposide for refractory neuroblastoma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Stem Cells
/
Bone Marrow
/
Administration, Oral
/
Salvage Therapy
/
Drug Therapy
/
Etoposide
/
Neuroblastoma
Language:
Korean
Journal:
Korean Journal of Pediatric Hematology-Oncology
Year:
2003
Type:
Article
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