Mast Cell Degranulation with Special Reference to the Effect of a Saponin Extract of Ginseng upon the Mesenteric Mast Cell of Albino Rats
Yonsei Medical Journal
;
: 1-5, 1963.
Article
in English
| WPRIM
| ID: wpr-11529
ABSTRACT
Water extract of dried ginseng, which is known as a histamine liberator and induces degranulation and disruption of mesenteric mast cells, is thought to contain many different chemical factors. The essential component, a saponin extract of dried ginseng, was obtained and administered to albino rats. Even minute amounts (l mg in 0.0l cc of normal saline solution) when locally injected into the mesentery of albino rats caused degranulation of mesenteric mast cells. Degranulation of mesenteric mast cells followed the intraperitoneal injection of a crude water extract, of an alcohol extract of dried ginseng, and a direct injection of both extracts into the connective tissue of mesentery. This degranulation is believed to be a saponin fraction of ginseng in the ginseng extracts.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plants, Medicinal
/
Saponins
/
Panax
/
Mast Cells
Limits:
Animals
Language:
English
Journal:
Yonsei Medical Journal
Year:
1963
Type:
Article
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