Bactericidal Effect of Disinfectant Tego-51(R) / 병원감염관리
Korean Journal of Nosocomial Infection Control
;
: 55-59, 1997.
Article
in Korean
| WPRIM
| ID: wpr-115299
ABSTRACT
BACKGROUND:
Disinfection is essential for the prevention of hospital infoction. Tego-51, one of the amphoteric surfactants based on the dodecyl-di( aminoethyl)-glycine, has been considered as an effctive disinfectant having a broad specturn of antimicrobial activity. We evaluated the disinfective activity of Tego-51 against several clinical isolates of bacteria and yeasts including Helicobacter pyiori.METHODS:
Twenty three strains of vacteria including H. pylori, and a strain of yeast were exposed to the various concentrations (0.05%, 0.01%, 0.005%) of Tego-51 for the various periods (0.5, 1, 2, 4, 8, 16min). After the exposure to Tego-51 disinfectant, 0.01 mL of mixture of microorfanisms and Tego-51 was inoculated into brain-heart infusion broth, into Sabouraud dextrose agar. or Wilkins-Chalgren agar with 10% sheep blood, and incubated at 37 degrees C for 48 hours or in the Campy Pouch microaerophilic system.RESULTS:
Most strains were killed within 30 seconds after an exposure to 0.01% of Tego-51, but Proteus mirabilis was eradicated after two minutes of exposure. At the concentration of 0.005 % concentration. P. mirabilis and Bacillus subtilis were killed after eight minutes od exposure. H. pylori was killed with 0.005% Tego-51within 30 seconds. Conslusions This study showed that Tego-51disinfectant was effective for the disinfection of commonly isolated bacteria and yeast from hospital. It may be recommended that Tego-51 should be used at concentration greater than 0.1% for the effective disinfection of skin, instruments and hospital floors.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Proteus mirabilis
/
Skin
/
Surface-Active Agents
/
Bacillus subtilis
/
Bacteria
/
Yeasts
/
Sheep
/
Disinfection
/
Cross Infection
/
Helicobacter
Language:
Korean
Journal:
Korean Journal of Nosocomial Infection Control
Year:
1997
Type:
Article
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