Short-course palliative radiotherapy for uterine cervical cancer
Radiation Oncology Journal
;
: 216-221, 2013.
Article
in English
| WPRIM
| ID: wpr-115565
ABSTRACT
PURPOSE:
The purpose of this retrospective study was to evaluate the efficacy and feasibility of short-course hypofractionated radiotherapy (RT) for the palliation of uterine cervical cancer. MATERIALS ANDMETHODS:
Seventeen patients with cancer of the uterine cervix, who underwent palliative hypofractionated 3-dimensional conformal radiotherapy between January 2002 and June 2012, were retrospectively analyzed. RT was delivered to symptomatic lesions (both the primary mass and/or metastatic regional lymph nodes). The total dose was 20 to 25 Gy (median, 25 Gy) in 5 Gy daily fractions.RESULTS:
The median follow-up duration was 12.2 months (range, 4 to 24 months). The median survival time was 7.8 months (range, 4 to 24 months). Vaginal bleeding was the most common presenting symptom followed by pelvic pain (9 patients). The overall response rates were 93.8% and 66.7% for vaginal bleeding control and pelvic pain, respectively. Nine patients did not have any acute side effects and 7 patients showed minor gastrointestinal toxicity. Only 1 patient had grade 3 diarrhea 1 week after completion of treatment, which was successfully treated conservatively. Late complications occurred in 4 patients; however, none of these were of grade 3 or higher severity.CONCLUSION:
Short-course hypofractionated RT was effective and well tolerated as palliative treatment for uterine cervical cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Palliative Care
/
Radiotherapy
/
Uterine Hemorrhage
/
Uterine Cervical Neoplasms
/
Cervix Uteri
/
Retrospective Studies
/
Follow-Up Studies
/
Pelvic Pain
/
Radiotherapy, Conformal
/
Diarrhea
Type of study:
Observational study
/
Prognostic study
Limits:
Female
/
Humans
Language:
English
Journal:
Radiation Oncology Journal
Year:
2013
Type:
Article
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