A Case of Reactive Airways Dysfunction Syndrome in a Synthetic Resin Manufacture Factory / 대한산업의학회지
Korean Journal of Occupational and Environmental Medicine
;
: 372-378, 2008.
Article
in Korean
| WPRIM
| ID: wpr-115618
ABSTRACT
BACKGROUND:
Reactive airways dysfunction syndrome (RADS), which represents between 5% and 18% of new-onset, work-related asthma, remains underreported in spite of increasing reports of occupational asthma cases through occupational asthma surveillance in Korea. We report a 61-year-old male who developed RADS after exposure to a high level of toxic gases from a workplace accident. CASE The patient who had worked for 21 years at a PVC manufacture factory and had retained good health until Aug 22, 2007, when he was exposed to PVC (polyvinyl chloride), DEHP (Di (2-Ethylhexyl) Phthalate), dibutyl tin maleate and epoxidized soybean oil gases from a heated mixer. Within several minutes of exposure, he developed coughing, rhinorrhea, dyspnea and wheezing. Pulmonary function tests (PFTs) showed an FVC of 3.81 L(82% of predicted), FEV1 of 1.63 L/s (50% of predicted), FEV1/FVC% of 43 %, and FEV1 of 1.80 L/s that increased by 170 ml and 10.4% in response to bronchodilator. After 7 months of treatment with inhaled steroids and bronchodilators, repeat PFTs showed an FVC of 6.56 L(143.5% of predicted), FEV1 of 3.21 L(99.3% of predicted), and FEV1/FVC% of 48.9%. A methacholine challenge test was negative at a concentration of 25 mg/ml.CONCLUSION:
RADS occurred due to exposure to raw material vapors or their thermal decomposition products.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polyvinyl Chloride
/
Resins, Synthetic
/
Respiratory Function Tests
/
Asthma
/
Steroids
/
Tin
/
Soybean Oil
/
Bronchodilator Agents
/
Respiratory Sounds
/
Methacholine Chloride
Limits:
Humans
/
Male
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Journal of Occupational and Environmental Medicine
Year:
2008
Type:
Article
Similar
MEDLINE
...
LILACS
LIS