A Case of Leukoderma Punctata after Topical PUVA Therapy in Segmental Vitiligo Patient / 대한피부과학회지
Korean Journal of Dermatology
;
: 190-192, 2006.
Article
in Korean
| WPRIM
| ID: wpr-11590
ABSTRACT
Leukoderma punctata is a rare side effect of photochemotherapy such as psoralen with solar ultraviolet light (PUVASOL) or psoralen with ultraviolet A (PUVA), and manifests as numerous discrete punctate, hypopigmented and achromic spots. Histopathologically, a focal reduction of melanocytes and melanin granules are found in the depigmented macules, revealed by S-100 and Fontana-Masson staining. The phototoxic effect of photochemotherapy on melanocytes has been suggested as the most likely cause. This occurs mostly after systemic psoralen on photochemotherapy. However, a case following topical PUVA therapy is very rare. We report a rare case of leukoderma punctata in a 6-year-old female after topical PUVA therapy for segmental vitiligo.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Photochemotherapy
/
PUVA Therapy
/
Ultraviolet Rays
/
Vitiligo
/
Ficusin
/
Melanins
/
Melanocytes
Limits:
Child
/
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2006
Type:
Article
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