Activities of Serum Lactate Dehydrohenase and Lactate Dehydrogenase Isoenzymes Activities by Small Opacity Groups on Chest Radiographs in Coal Worker's Pneumoconiosis Patients / 대한산업의학회지
Korean Journal of Occupational and Environmental Medicine
;
: 206-211, 1990.
Article
in Korean
| WPRIM
| ID: wpr-116220
ABSTRACT
Serum lactate degydrogenase (LD) and LD isoenzyme activities were evaluated in sera from 74 patients of coal workers' pneumoconiosis (CWP) to investigate biochemical changes of these enzyme activities according to radiographical profusions of CWP. Subjects were participated patients in the detailed examination of pneumoconiosis in December 1989. LD activities were evaluated by lactate to pyruvate methods and isoenzyme activities were determined by agarose gel electrophoresis. And small opacity profusions on chest radiographs of subjects were evaluated by radiologist. The results were as follows 1. LD activities were not significantly different among categories of radiographical profusions. 2. LD4 activities were shown difference significantly among categories of radiographical profusions (category 1 8.2+/-2.69 U/l, category 2 10.1+/-3.90, category 3 10.6+/-2.63; p<0.05). 3. Activities of LD(1), LD(2), LD(3), and LD(5) were not different significantly among categories of radiographical profusions. Conclusionly, serum LD(4) activity seems to be increased by fibroplasia of CWP, but increasing activities of LD4 should not affect serum LD activities significantly.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pneumoconiosis
/
Thorax
/
Radiography, Thoracic
/
Coal
/
Lactic Acid
/
Pyruvic Acid
/
Electrophoresis, Agar Gel
/
Anthracosis
/
Isoenzymes
/
L-Lactate Dehydrogenase
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Occupational and Environmental Medicine
Year:
1990
Type:
Article
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