A case of lymphomatoid contact dermatitis caused by garlic / 천식및알레르기
Journal of Asthma, Allergy and Clinical Immunology
;
: 548-552, 2003.
Article
in Korean
| WPRIM
| ID: wpr-116899
ABSTRACT
Garlic(Allium sativum) is recognized as a sensitizing agent responsible for allergic contact dermatitis with food handlers and housewives. Lymphomatoid contact dermatitis, which is a type of allergic contact dermatitis, shows similar histologic features to Mycosis Fungoides. We report a 66-year-old male, who had applied garlic extract to both lower extremities and the trunk for 8 months for relieving his symptoms of arthralgia and generalized pruritis. He had complained of variable sized multiple erythematous pruritic papules on both lower extremities and the trunk and lymphadenopathy of both inguinal and axillary area. Skin biopsy was performed and the histological exam presented microscopically abnormal lymphocyte infiltration in the upper dermis. T-cell marker studies revealed strong CD3 positivity and increased CD4/CD8 ratio. The results of PCR-heteroduplex analysis showed negative for T-cell receptor- gene rearrangement and abscence of T-cell monoclonality. We could diagnose his skin lesion and generalized lymphadenopathy as lymphomatoid contact dermatitis which represented as a T-cell pseudolymphoma histologically. He was treated with local steroid injection and phototherapy and the skin lesion were improved without recurrence.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phototherapy
/
Pruritus
/
Recurrence
/
Skin
/
Biopsy
/
Lymphocytes
/
T-Lymphocytes
/
Gene Rearrangement
/
Mycosis Fungoides
/
Dermatitis, Allergic Contact
Limits:
Aged
/
Humans
/
Male
Language:
Korean
Journal:
Journal of Asthma, Allergy and Clinical Immunology
Year:
2003
Type:
Article
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