Fetal Nuchal Translucency Measurement for Detection of Chromosomal Abnormalities in the First Trimester of High Risk Pregnancy / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology
;
: 2739-2742, 1998.
Article
in Korean
| WPRIM
| ID: wpr-116993
ABSTRACT
OBJECTIVE:
To determine the value of sonographic nuchal translucency measurement for the detection of chromosomal abnormalities in high risk pregnancies.METHOD:
The feasibility of nuchal translucency was tested in a prospective study of 1260 pregnancies at 10- 13 weeks' gestation.RESULTS:
The nuchal translucency of 3 mm or greater was identified in 41 fetuses (3.2%), 19 of whom proved subsequently by either amniocentesis or postnatal follow-up have chromosomal abnormalities. The sensitivity of nuchal translucency for chromosomal abnormalities was 82.6% (19 of 23 cases), the positive predictive value of nuchal translucency for chromosomal abnormalities detection was 46.3% (19 of 41 cases).CONCLUSION:
The observed sensitivity, false-positive rate and predictive value suggest that sonographic nuchal translucency should be undertaken at 10 to 13 weeks of gestation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pregnancy Trimester, First
/
Prospective Studies
/
Follow-Up Studies
/
Chromosome Aberrations
/
Ultrasonography
/
Pregnancy, High-Risk
/
Nuchal Translucency Measurement
/
Fetus
/
Amniocentesis
Type of study:
Diagnostic study
/
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
/
Pregnancy
Language:
Korean
Journal:
Korean Journal of Obstetrics and Gynecology
Year:
1998
Type:
Article
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