Toxic Epidermal Necrolysis Induced by the Topical Carbonic Anhydrase Inhibitors Brinzolamide and Dorzolamide
Annals of Dermatology
;
: 260-262, 2008.
Article
in English
| WPRIM
| ID: wpr-117019
ABSTRACT
Brinzolamide and dorzolamide are highly specific topical carbonic anhydrase inhibitors (CAIs). They lower intraocular pressure (IOP) by reducing the rate of aqueous humour formation without serious side effects. Although systemic CAIs are the most potent medications for lowering intraocular pressure for conditions with ocular hypertension, many cases with adverse systemic reactions have been reported, including Stevens-Johnson syndrome (SJS) and Toxic epidermal necrolysis (TEN). Here, we report 2 cases of TEN that were associated with topical CAIs rather than systemic CAIs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sulfonamides
/
Thiazines
/
Thiophenes
/
Carbon
/
Carbonic Anhydrase Inhibitors
/
Ocular Hypertension
/
Stevens-Johnson Syndrome
/
Carbonic Anhydrases
/
Intraocular Pressure
Language:
English
Journal:
Annals of Dermatology
Year:
2008
Type:
Article
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