T Cells in Cutaneous Lesions of Psoriasis / 대한피부과학회지
Korean Journal of Dermatology
;
: 279-282, 1985.
Article
in Korean
| WPRIM
| ID: wpr-117084
ABSTRACT
Anti-T cell monoclonal antibodies(OKT series OKT4a OKT8A, OKT1 1) ir,amunoperoxidase technique studies were performed for the presence of T cells and their subpopulations in cutaneous lesions of early papules and late plaques from 10 patients with psoriasis. In this semiquantitative examination, T cells reactive to OKT11 antiserum constituted about 70 percents of total leukocytes found in the dermis, both in early papular lesions and late plaque lesions. The number of helper/inducer T cells was about equal to the number of suppressor/cytotoxic T cells in early papular lesions, but helper/inducer T cells were predominant in plaque lesions. Although in situ functions of T cell and their subpopulations can not precisely be deduced, this different proportions of the helper/inducer and suppressor/cytotoxic T cells found in this study might be related to the immunopathologic mechanisms pertainmg to the persistence and the expansion of psoriatic lesions.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Psoriasis
/
T-Lymphocytes
/
Dermis
/
Leukocytes
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
1985
Type:
Article
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