Three Cases of Functioning Adrenocortical Tumor

ABSTRACT

Neoplasms of the adrenal cortex are rare in children. Some of them are functioning malignant neoplasms. Two girls with variable degree of virilization and Cushing's sydnrome and a boy with only Cushing's syndrome, which were due to functioning adrenocortical tumors, were presented. All iesions were found in the left adrenal gland. Two of them were histologically adrenocortical calcinoma. There was no histological evidence of malignancy in the oter one in spite of considerable increasing of 24hrs urinary 17 kerosteroid excretion. A review of literature was also made.