A case of lymphoepithelioma-like carcinoma of the uterine cervix / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology
;
: 207-211, 2007.
Article
in Korean
| WPRIM
| ID: wpr-117916
ABSTRACT
Lymphoepithelioma-like carcinoma (LELC) of the uterine cervix is a rare tumor with 0.7% of all primary cervical malignancies. It may grossly range from no visible cervical lesion to a large exophytic cervical mass and histologically similar neoplasms occur in the nasopharynx. It has been classified as a subtype of squamous cell carcinoma. But, after reviewing the literature, this tumor is a distinct carcinoma of the cervix that differs from squamous cell carcinoma. LELC is composed of undifferentiated cells surrounded by a marked inflammatory infiltrate, characterized by plasma cells and lymphocytes in the stroma. It may represent a better prognostic group than the more common squamous cell carcinoma of the cervix because of lack of lymph node metastasis. Typically affects a younger population of women, is more prevalent in noncaucasian population (especially, those of Asian descent). However, it is not clearly understood, Epstein-Barr virus play in the pathogenesis of cervical LELC while humam papilloma virus (HPV) is a risk factor for squamous cell carcinoma. The prognosis is good only by surgical treatment. Radiation therapy also appears to be effective in eradicating localized, low-stage disease (radiosensitive). The authors have experienced one case of LELC of the uterine cervix. We report a case with a brief review.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Papilloma
/
Plasma Cells
/
Prognosis
/
Lymphocytes
/
Carcinoma, Squamous Cell
/
Cervix Uteri
/
Nasopharynx
/
Risk Factors
/
Herpesvirus 4, Human
/
Asian People
Type of study:
Etiology study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Obstetrics and Gynecology
Year:
2007
Type:
Article
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