Genomic Basis for Methicillin Resistance in Staphylococcus aureus / 감염과화학요법
Infection and Chemotherapy
;
: 117-136, 2013.
Article
in English
| WPRIM
| ID: wpr-118615
ABSTRACT
Since the discovery of the first strain in 1961 in England, MRSA, the most notorious multidrug-resistant hospital pathogen, has spread all over the world. MRSA repeatedly turned down the challenges by number of chemotherapeutics, the fruits of modern organic chemistry. Now, we are in short of effective therapeutic agents against MRSA prevailing among immuno-compromised patients in the hospital. On top of this, we recently became aware of the rise of diverse clones of MRSA, some of which have increased pathogenic potential compared to the classical hospital-associated MRSA, and the others from veterinary sources. They increased rapidly in the community, and started menacing otherwise healthy individuals by causing unexpected acute infection. This review is intended to provide a whole picture of MRSA based on its genetic makeup as a versatile pathogen and our tenacious colonizer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sprains and Strains
/
Staphylococcus
/
Staphylococcus aureus
/
Adenosine
/
Chemistry, Organic
/
Methicillin Resistance
/
Clone Cells
/
Colon
/
Chromatography, Micellar Electrokinetic Capillary
/
England
Limits:
Humans
Country/Region as subject:
Europa
Language:
English
Journal:
Infection and Chemotherapy
Year:
2013
Type:
Article
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