Serum CA 19-9 levels in patients with endometriosis / 대한산부인과학회잡지

ABSTRACT

OBJECTIVE: To explore the efficacy of serum CA19-9 determination for the detection of endometriosis. DESIGNS A retrospective analysis. MATERIALS AND METHODS: Preoperative serum CA19-9 and CA125 concentrations were measured in 53 patients with surgically and/or histologically diagnosed endometriosis. The extent of disease was staged according to the revised American Fertility Society (1985) classification system. RESULTS: Serum CA19-9 levels were elevated (>or=37 U/ml) in 13 (24.5%) out of 53 patients with endometriosis and serum CA125 levels were elevated (>or=35 U/ml) in 13 (24.5%). Either CA19-9 or CA125 levels in serum were elevated in 18 (34.0%) patients. In patients with stage III or IV endometriosis, elevated CA19-9 levels were noted in 11 (31.4%) of 35 patients, while CA125 in 12 (34.3%). Either CA19-9 or CA125 levels in serum were elevated in 15 (42.9%) of 35 patients with stage III or IV. CONCLUSION: These results suggest that serum CA19-9, in addition to CA125, measurement could help in identifying patients with moderate to severe endometriosis.