Risk Factors and Outcome of Nephrocalcinosis in Very Low Birth Weight Infants / 대한주산의학회잡지
Korean Journal of Perinatology
;
: 35-45, 2015.
Article
in English
| WPRIM
| ID: wpr-118870
ABSTRACT
PURPOSE:
The aim of this study was to determine the incidence, risk factors, and long-term outcome of nephrocalcinosis in very low birth weight (VLBW) infants.METHODS:
A retrospective chart review was performed in VLBW infants between 2006 and 2012 in the neonatal intensive care unit.RESULTS:
The incidence of nephrocalcinosis in VLBW infants was 10.2%. By univariate analysis, oligohydramnios and use of antenatal steroids were more frequent in the nephrocalcinosis group. In the nephrocalcinosis group, the gestational age and birth weight were lower and there were more number of female infants. Also, the initial blood pH, the lowest systolic blood pressure, and urine output on the first day of life were lower and bronchopulmonary dysplasia, sepsis, and urinary tract infection were more prevalent in the nephrocalcinosis group. The use of dexamethasone or ibuprofen and the lowest levels of phosphorus, protein and albumin were significantly lower in the nephrocalcinosis group. By binary logistic regression analysis, the use of antenatal steroids, female sex, 5-minute Apgar score, duration of oxygen therapy and total parenteral nutrition, and the lowest albumin level were found to be significant risk factors for nephrocalcinosis. Overall, the resolution rate was 64.1% and 88.6% within 12 months and 18 months, respectively.CONCLUSION:
The incidence of nephrocalcinosis in VLBW infants showed increasing trend. The risk factors of nephrocalcinosis were parameters for sick VLBW infants. Although the prognosis of nephrocalcinosis was relatively good, we should pay close attention to the development of complication.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oxygen
/
Apgar Score
/
Phosphorus
/
Prognosis
/
Steroids
/
Urinary Tract Infections
/
Birth Weight
/
Blood Pressure
/
Bronchopulmonary Dysplasia
/
Dexamethasone
Type of study:
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
Limits:
Female
/
Humans
/
Infant
/
Infant, Newborn
/
Pregnancy
Language:
English
Journal:
Korean Journal of Perinatology
Year:
2015
Type:
Article
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