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Effects of Percutaneous Coronary Intervention on Depressive Symptoms in Chronic Stable Angina Patients
Psychiatry Investigation ; : 252-256, 2012.
Article in English | WPRIM | ID: wpr-119422
ABSTRACT

OBJECTIVE:

Depression is present in 1 of 5 outpatients with coronary artery disease (CAD), and a well-documented risk factor for recurrent cardiac events and mortality. We examined the impact of percutaneous coronary intervention (PCI), on depressive symptoms, in chronic stable angina (CSA) patients.

METHODS:

On prospective and non-randomized trial, consecutive CSA patients (n=171), who had undergone coronary angiography from January 2006 to December 2007, were included. Patients were subdivided into PCI and non-PCI groups, and then completed 21-item the Beck Depression Inventory II (BDI-II), at the baseline and pre-discharge, to assess the depressive symptoms.

RESULTS:

A total of 108 (63%) patients were assigned to the non-PCI group, and 63 (37%) patients to the PCI group. Using an independent t-test, we found that patients with PCI were significantly older (non-PCI vs. PCI; 57+/-11 vs. 64+/-10, years, p<0.001), had more joint disease (12.0 vs. 27.0%, p=0.013), more stroke history (5.6 vs. 17.5%, p=0.012) and higher incident of family history of cardiovascular disease (28.7 vs. 46.0%, p=0.025), but less religion (54.6 vs. 36.5%, p=0.002) and private health insurance (43.5 vs. 20.6%, p=0.002). The mean difference of BDI-II score between the baseline and pre-discharge was higher in patients with PCI (OR 1.266; 95% CI 1.146-1.398, p<0.001).

CONCLUSION:

In conclusion, PCI contributes independently to higher risk of developing depressive symptoms in CSA patients during hospitalization; Routine assessment and management of PCI related depressive symptoms are justified.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Outpatients / Coronary Artery Disease / Cardiovascular Diseases / Prospective Studies / Risk Factors / Coronary Angiography / Angioplasty / Stroke / Depression / Angina, Stable Type of study: Controlled clinical trial / Diagnostic study / Etiology study / Observational study / Risk factors Limits: Humans Language: English Journal: Psychiatry Investigation Year: 2012 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Outpatients / Coronary Artery Disease / Cardiovascular Diseases / Prospective Studies / Risk Factors / Coronary Angiography / Angioplasty / Stroke / Depression / Angina, Stable Type of study: Controlled clinical trial / Diagnostic study / Etiology study / Observational study / Risk factors Limits: Humans Language: English Journal: Psychiatry Investigation Year: 2012 Type: Article