Effect of Stimulation Polarity of Transcranial Direct Current Stimulation on Non-dominant Hand Function
Annals of Rehabilitation Medicine
;
: 1-7, 2012.
Article
in English
| WPRIM
| ID: wpr-119608
ABSTRACT
OBJECTIVE:
To evaluate motor excitability and hand function on the non-dominant side according to the polarity of transcranial direct current stimulation (tDCS) on the motor cortex in a healthy person.METHOD:
tDCS was applied to the hand motor cortex for 15 minutes at an intensity of 1 mA in 28 healthy right-handed adults. Subjects were divided randomly into four groups an anodal tDCS of the non-dominant hemisphere group, a cathodal tDCS of the non-dominant hemisphere group, an anodal tDCS of the dominant hemisphere group, and a sham group. We measured the motor evoked potential (MEP) in the abductor pollicis brevis and Jabsen-Taylor hand function test (JTT) in the non-dominant hand prior to and following tDCS. All study procedures were done under double-blind design.RESULTS:
There was a significant increase in the MEP amplitude and a significant improvement in the JTT in the non-dominant hand following anodal tDCS of the non-dominant hemisphere (p<0.05). But there was no change in JTT and a significant decrease in the MEP amplitude in the non-dominant hand following cathodal tDCS on the non-dominant hemisphere and anodal tDCS of the dominant hemisphere.CONCLUSION:
Non-dominant hand function is improved by increased excitability of the motor cortex. Although motor cortex excitability is decreased in a healthy person, non-dominant hand function is maintained. A homeostatic mechanism in the brain might therefore be involved in preserving this function. Further studies are warranted to examine brain functions to clarify this mechanism.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Brain
/
Salicylamides
/
Evoked Potentials, Motor
/
Hand
/
Motor Cortex
Type of study:
Controlled clinical trial
Limits:
Adult
/
Humans
Language:
English
Journal:
Annals of Rehabilitation Medicine
Year:
2012
Type:
Article
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