Effect of a Diet with Unrestricted Sodium on Ascites in Patients with Hepatic Cirrhosis
Gut and Liver
;
: 355-361, 2012.
Article
in English
| WPRIM
| ID: wpr-119849
ABSTRACT
BACKGROUND/AIMS:
There has been debate on whether a sodium-restricted diet (SRD) should be used in cirrhotic patients with ascites in China in recent years. The purpose of this study was to compare the effect of sodium-restricted and unrestricted diets on plasma renin activity (PRA), renal blood flow (RBF) and ascites in patients with liver cirrhosis.METHODS:
Two hundred cirrhotic patients with ascites were randomly divided into two groups (98 cases in the sodium-unrestricted diet [SUD] group and 102 cases in the SRD group); 95 patients (96.94%) in the SUD group and 97 patients (95.1%) in the SRD group had post-hepatitis B cirrhosis.RESULTS:
Blood sodium and RBF were higher in SUD group than in SRD group (p<0.001), while PRA were significantly lower in SUD group than the SRD group 10 days after treatment (p<0.001). Renal impairment caused by low blood sodium was higher in SRD group than in SUD group (p<0.01). Ascites disappeared in higher proportion of patients in SUD group than in SRD group (p<0.001).CONCLUSIONS:
SUD can increase the level of blood sodium and RBF, and be beneficial to diuresis and ascite reduction and disappearance.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plasma
/
Ascites
/
Renal Circulation
/
Sodium
/
China
/
Renin
/
Diet
/
Diet, Sodium-Restricted
/
Diuresis
/
Liver
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Gut and Liver
Year:
2012
Type:
Article
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