The Effects of Serum Homocysteine on the Restenosis after Percutaneous Coronary Intervention
Korean Circulation Journal
;
: 560-566, 2001.
Article
in Korean
| WPRIM
| ID: wpr-120479
ABSTRACT
BACKGROUND AND OBJECTIVES:
Hyperhomocyt(e)inemia is known to be one of independent risk factors for the ischemic heart diseases recently, but the role of hyperhomocysteinemia in restenosis after coronary intervention is unclear. The relationship between plasma homocysteine level and restenosis after coronary intervention was evaluated in Korean patients. MATERIALS ANDMETHOD:
Eighty three patients underwent successful percutaneous coronary intervention (PCI) and follow-up coronary angiography were divided into two groups according to restenosis, and the level of plasma homocysteine was compared between groups with restenosis (n=5, MF=78, 60.6+/-13.5 years) and without restenosis (n=8, MF=08, 60.3+/-12.8 years).RESULTS:
The clinical manifestation, atherosclerosis risk factors except for hypertension, and coronary angiographic findings were not significantly different in patients with or without restenosis(P=S). The value of homocysteine was 9.3+/-3.1 micromol/L in 35 patients with restenosis and 8.4+/-2.5 micromol/L in 48 patients without restenosis(P=S). All of 8 patients whose values of plasma homocysteine were more than 13 micromol/L, had angiographic restenosis. Plasma homocysteine was not an independent risk factor of restenosis by means of logistic regression analysis.CONCLUSION:
Plasma homocysteine is not a potential risk factor of restenosis after percutaneous coronary intervention.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plasma
/
Logistic Models
/
Risk Factors
/
Follow-Up Studies
/
Coronary Angiography
/
Myocardial Ischemia
/
Hyperhomocysteinemia
/
Atherosclerosis
/
Percutaneous Coronary Intervention
/
Homocysteine
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
Korean
Journal:
Korean Circulation Journal
Year:
2001
Type:
Article
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