The Estimated Glomerular Filtration Rate With Using the Mayo Clinic Quadratic Equation as a New Predictor for Developing Contrast Induced Nephropathy in Patients With Angina Pectoris

ABSTRACT

BACKGROUND AND OBJECTIVES: The Mayo clinic quadratic (MCQ) glomerular filtration rate (GFR) equation accurately estimates the GFR when the presence of kidney disease is unknown. The aim of this study is to evaluate the usefulness of the MCQ GFR equation for predicting contrast-induced nephropathy (CIN) in patients with angina pectoris and who are undergoing coronary angiography (CAG) or percutaneous coronary intervention (PCI). SUBJECTS AND METHODS: One hundred seven patients diagnosed with stable or unstable angina and who had normal serum creatinine levels (SCr or =250 mL (OR 17.1, p=0.002), a CRP level > or =0.5 mg/dL (OR 4.7, p=0.037) and a left ventricular ejection fraction < or =40% (OR 1.7, p=0.020) were the independent risk factors for CIN. CONCLUSION: The pre-coronary angiography MCQ GFR is a useful predictor for the development of CIN. Strong preventive strategies are needed to avoid developing CIN in these high-risk patients.