Differentiation between Benign and Malignant Solid Thyroid Nodules Using an US Classification System
Korean Journal of Radiology
;
: 559-567, 2011.
Article
in English
| WPRIM
| ID: wpr-121840
ABSTRACT
OBJECTIVE:
To evaluate the diagnostic accuracy of a new ultrasound (US) classification system for differentiating between benign and malignant solid thyroid nodules. MATERIALS ANDMETHODS:
In this study, we enrolled 191 consecutive patients who received real-time US and subsequent US diagnoses for solid thyroid nodules, and underwent US-guided fine-needle aspiration. Each thyroid nodule was prospectively classified into 1 of 5 diagnostic categories by real-time US "malignant," "suspicious for malignancy," "borderline," "probably benign," and "benign". We evaluated the diagnostic accuracy of thyroid US and the cut-off US criteria by comparing the US diagnoses of thyroid nodules with cytopathologic results.RESULTS:
Of the 191 solid nodules, 103 were subjected to thyroid surgery. US categories for these 191 nodules were malignant (n = 52), suspicious for malignancy (n = 16), borderline (n = 23), probably benign (n = 18), and benign (n = 82). A receiver-operating characteristic curve analysis revealed that the US diagnosis for solid thyroid nodules using the 5-category US classification system was very good. The sensitivity, specificity, positive and negative predictive values, and accuracy of US diagnosis were 86%, 95%, 91%, 92%, and 92%, respectively, when benign, probably benign, and borderline categories were collectively classified as benign (negative).CONCLUSION:
The diagnostic accuracy of thyroid US for solid thyroid nodules is high when the above-mentioned US classification system is applied.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thyroid Neoplasms
/
Predictive Value of Tests
/
Sensitivity and Specificity
/
Thyroid Nodule
/
Ultrasonography, Interventional
/
Cytodiagnosis
/
Biopsy, Fine-Needle
/
Diagnosis, Differential
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Korean Journal of Radiology
Year:
2011
Type:
Article
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