Influence of Droperidol on Postoperative Nausea and Vomiting during Patient-Controlled Analgesia with Fentanyl / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 132-136, 1998.
Article
in Korean
| WPRIM
| ID: wpr-12204
ABSTRACT
INTRODUCTION:
Patient-controlled analgesia (PCA) has become an important means for postoperative analgesia with parenteral opioid, but postoperative nausea and vomiting (PONV) remains a major problem using a PCA system. The present study was designed to assess the antiemetic effectiveness of droperidol in patients using an intravenous PCA during the first 24 hours after surgery.METHODS:
For the postoperative analgesia, 80 patients underwent orthopedic surgery were randomly allocated to receive PCA with either a mixture of 3.75 mg droperidol and fentanyl 2500 microgram after initial bolus of 1.25 mg droperidol as the FD group, or a mixture of saline and fentanyl 2500 microgram as the FS group at the end of surgery.RESULTS:
The incidence of PONV showed 52.5% in FS group and 15% in FD group respectively (P<0.05). The incidence of PONV was 2~3 times more in women (76% in FS group & 25% in FD group) than men (35% in FS group & 9% in FD group).CONCLUSION:
The addition of droperidol to fentanyl in a PCA system reduces the PONV during the first 24 hours after surgery.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Orthopedics
/
Passive Cutaneous Anaphylaxis
/
Fentanyl
/
Incidence
/
Analgesia, Patient-Controlled
/
Postoperative Nausea and Vomiting
/
Droperidol
/
Analgesia
/
Antiemetics
Type of study:
Incidence study
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Anesthesiology
Year:
1998
Type:
Article
Similar
MEDLINE
...
LILACS
LIS