Stage-specific embryonic antigen: determining expression in canine glioblastoma, melanoma, and mammary cancer cells
Journal of Veterinary Science
;
: 101-104, 2017.
Article
in English
| WPRIM
| ID: wpr-122304
ABSTRACT
The expression of stage-specific embryonic antigens (SSEAs) was determined in several types of canine cancer cells. Flow cytometry showed SSEA-1 expression in glioblastoma, melanoma, and mammary cancer cells, although none expressed SSEA-3 or SSEA-4. Expression of SSEA-1 was not detected in lymphoma, osteosarcoma, or hemangiosarcoma cell lines. Relatively stable SSEA-1 expression was observed between 24 and 72 h of culture. After 8 days in culture, sorted SSEA-1⁻ and SSEA-1⁺ cells re-established SSEA-1 expression to levels comparable to those observed in unsorted cells. Our results document, for the first time, the expression of SSEA-1 in several canine cancer cell lines.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Breast Neoplasms
/
Osteosarcoma
/
Cell Line
/
Lewis X Antigen
/
Glioblastoma
/
Stage-Specific Embryonic Antigens
/
Flow Cytometry
/
Hemangiosarcoma
/
Lymphoma
/
Melanoma
Language:
English
Journal:
Journal of Veterinary Science
Year:
2017
Type:
Article
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