Treatment of Dysphagia with Pyridostigmine Bromide in a Patient with the Pharyngeal-Cervical-Brachial Variant of Guillain-Barre Syndrome
Annals of Rehabilitation Medicine
;
: 148-153, 2012.
Article
in English
| WPRIM
| ID: wpr-122691
ABSTRACT
A 24-year-old male developed bulbar palsy, ophthalmoplegia, ptosis, and shoulder weakness bilaterally 2 weeks after he had experienced an upper respiratory infection. The electrodiagnostic study demonstrated axonal polyradiculoneuropathy. The repetitive nerve stimulation study (RNS) showed no significant decrement of the compound muscle action potentials (CMAPs). The videofluoroscopic swallowing study (VFSS) showed severe impairment of the pharyngeal phase of swallowing. He was diagnosed as having the pharyngeal-cervical-brachial variant of Guillain-Barre syndrome. The patient's dysphagia was not improved for 3 months. A follow up RNS showed a significant decrement of the CMAPs. Pyridostigmine bromide was tried to improve the dysphagia. The patient showed immediate improvement of his dysphagia on the VFSS after the trial with pyridostigmine bromide. Pyridostigmine bromide was given before each meal for 8 days and he showed continuous improvement of his dysphagia. The follow up VFSS after 3 months showed complete recovery of dysphagia.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Bulbar Palsy, Progressive
/
Polyradiculoneuropathy
/
Pyridostigmine Bromide
/
Shoulder
/
Axons
/
Action Potentials
/
Deglutition Disorders
/
Ophthalmoplegia
/
Follow-Up Studies
/
Guillain-Barre Syndrome
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
/
Male
Language:
English
Journal:
Annals of Rehabilitation Medicine
Year:
2012
Type:
Article
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