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A Case of Carcinoid Syndrome with a Scleroderma-like Lesion / 대한피부과학회지
Korean Journal of Dermatology ; : 1054-1059, 2009.
Article in Korean | WPRIM | ID: wpr-122769
ABSTRACT
Carcinoid syndrome exhibits a constellation of symptoms typically exhibited by patients with carcinoid tumors that produce neuroendocrine mediators, including serotonin. Carcinoid syndrome is diagnosed by increasing urinary 5-hydroxyindoleacetic acid and manifestations of gastrointestinal tract, respiratory, cardiovascular, and skin involvement, which occurs in <10% of patients. Cutaneous manifestations are flushing, telangiectasias, pellagra dermatitis, and scleroderma-like lesions, which are relatively rare. A 60-year-old woman presented with sclerotic skin lesions on both legs. On examination, a 10x10 cm solid mass was palpable on the right lower abdomen, and she had facial flushing and telangiectasia, but Raynaud's phenomenon was absent. The urinary 5-hydroxyindoleacetic acid was elevated (68.2 mg/day). Abdominal and pelvic CT scans showed a right ovarian tumor which was diagnosed as a carcinoid tumor by CT-guided needle biopsy. Thus, we report, for the first time, a case of carcinoid syndrome with scleroderma-like lesions in a Korean patient. If facial flushing and a scleroderma-like lesion present together, one should consider a carcinoid tumor.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pellagra / Skin / Telangiectasis / Biopsy, Needle / Carcinoid Tumor / Serotonin / Gastrointestinal Tract / Dermatitis / Abdomen / Flushing Limits: Female / Humans Language: Korean Journal: Korean Journal of Dermatology Year: 2009 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pellagra / Skin / Telangiectasis / Biopsy, Needle / Carcinoid Tumor / Serotonin / Gastrointestinal Tract / Dermatitis / Abdomen / Flushing Limits: Female / Humans Language: Korean Journal: Korean Journal of Dermatology Year: 2009 Type: Article