Estimation of Paratuberculosis Prevalence in Dairy Cattle in a Province of Korea using an Enzyme-linked Immunosorbent Assay: Application of Bayesian Approach
Journal of Veterinary Science
;
: 51-56, 2003.
Article
in English
| WPRIM
| ID: wpr-122778
ABSTRACT
To draw inferences about the sensitivity and specificity of the newly developed ELISA test for bovine paratuberculosis (PTB) diagnosis and posterior distribution on the prevalence of PTB in a province of Korea, we applied Bayesian approach with Gibbs sampler to the data extracted from the prevalence study in 1999. The data were from a single test results without a designated gold test. The prevalence estimates for PTB in study population ranged 3.2~5.3% for conservative and 6.7~7.1% for liberal, depending on the priors used. The simulated specificities of the ELISA close to one another, ranging 84.7~90.6%, whereas the sensitivity was somewhat spread out depending largely on the priors with a range of 46.4~88.2%. Our findings indicate that the ELISA method appeared useful as a screening tool at a minimum level in comparison to other diagnostic tests available for this disease in terms of sensitivity. However, this advantage comes at a cost of having low specificity of the test.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Paratuberculosis
/
Enzyme-Linked Immunosorbent Assay
/
Cattle Diseases
/
Prevalence
/
Bayes Theorem
/
Korea
Type of study:
Prevalence study
/
Prognostic study
/
Risk factors
Limits:
Animals
Country/Region as subject:
Asia
Language:
English
Journal:
Journal of Veterinary Science
Year:
2003
Type:
Article
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