Study on pilot assay in manufacture of film coated tablet of ketoprofen with prolonged action
Pharmaceutical Journal
;
: 14-16, 2001.
Article
in Vietnamese
| WPRIM
| ID: wpr-1230
ABSTRACT
To obtain a prolonged-action dosage form of Ketoprofen, a technique for delaying drug release from insoluble inert matrix of ethyl cellulose was evaluated. It was incorporated with excipients such as lactose, starch, hydroxy propyl methyl cellulose. influence of lubricants on release profiles was also investigated. The best result was obtained from the formula that consists of ethyl cellulose, lactose, starch, hydroxy propyl methyl cellulose, magnesium stearate, talc, aerosil (appropriate rate) and is coated with Eudragit L 100 (1mg/cm2)
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Tablets
/
Pharmaceutical Preparations
/
Ketoprofen
/
Cyclooxygenase Inhibitors
Language:
Vietnamese
Journal:
Pharmaceutical Journal
Year:
2001
Type:
Article
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