Dexamethasone Administration and Propofol Anesthesia Prevent Postoperative Nausea and Vomiting / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 630-635, 1998.
Article
in Korean
| WPRIM
| ID: wpr-123388
ABSTRACT
BACKGROUND:
Nausea, vomiting are among the most common postoperative complaints. We compared the effects of dexamethasone with or without propofol to the effects of conventional regimen consisting of enflurane-N2O in the prevention of postoperative nausea and vomiting.METHODS:
Eighty healthy children, aged 3~14 yr, undergoing elective tonsillectomy were alldegrees Cated randomly to receive either 67% nitrous oxide and 1.5~2.0% enflurane or 67% nitrous oxide and propofol infusion 6~10 mg/kg/hr for maintenance of anesthesia. Dexamethasone 150 microgram/kg(maximum dose 8mg) or placebo was administered intrvenously(IV) in a double-blinded fashion before surgery.RESULTS:
Dexamethasone reduced the overall incidence of vomiting from 45%(control) to 10%, Propofol also reduced from 45% to 15%. Combination of propofol anesthesia and dexamethasone administration reduced from 45% to 10%.CONCLUSIONS:
Dexamethasone and propofol markedly decreased vomiting in healthy children after elective tonsillectomy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Tonsillectomy
/
Vomiting
/
Dexamethasone
/
Propofol
/
Incidence
/
Postoperative Nausea and Vomiting
/
Enflurane
/
Anesthesia
/
Nausea
/
Nitrous Oxide
Type of study:
Controlled clinical trial
/
Incidence study
/
Prognostic study
Limits:
Child
/
Humans
Language:
Korean
Journal:
Korean Journal of Anesthesiology
Year:
1998
Type:
Article
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