Fatal Hemophagocytic Lymphohistiocytosis associated with Influenza B / 대한내과학회지
Korean Journal of Medicine
;
: 88-91, 2016.
Article
in Korean
| WPRIM
| ID: wpr-123562
ABSTRACT
Influenza infection may be complicated by various infectious or non-infectious diseases. Among them, hemophagocytic lympho-histiocytosis (HLH) is an uncommon hyperinflammatory syndrome caused by uncontrolled proliferation and activation of macrophages and lymphocytes, and it is often life threatening. A previously healthy male patient was suspected to have HLH after influenza B infection. The diagnosis was established based on clinical diagnostic criteria suggested in the HLH-2004 trial. Despite prompt antiviral therapy, the patient expired on day 19 of hospitalization. Influenza can thus be complicated by HLH. Due to the non-specific manifestations of HLH, clinical suspicion and early diagnosis are important.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Lymphocytes
/
Early Diagnosis
/
Diagnosis
/
Lymphohistiocytosis, Hemophagocytic
/
Influenza, Human
/
Hospitalization
/
Macrophages
Type of study:
Diagnostic study
/
Screening study
Limits:
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2016
Type:
Article
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