Therapeutic Effect of 10 % Ginseng Saponin Ointment for Recurrent Herpes Simplex Virus Infections / 대한피부과학회지

ABSTRACT

Forty-two volunteers with recurrent herpes simplex virus infections were entolled in a clinical trial to evaluate the effectiveness of topical Ginseng saponin ointment. Ten percent Ginseng saponin in a water-micible ointment base was applied. 3 times daily until crust formation on 42 patients. As control hydrophilic ointment was applied 3 times daily on 10 patients. Auther compared the length of time required for the herpetic vesicles to form crust in these two groups. The time required in the group treated with Ginseng saponin for crust formation was 21.9+/-10.29 hours. In the control group it was 58.2+/-23.64 hours(P<0.01). There was no untoward effect to Ginseng saponin ointment. The Ginseng saponin ointment seems to be one of the best topieal antiviral agents in the treatment of recurrent herpes simplex virus infections.