The Effect of Desmopressin in Neurogenic Bladder due to Spinal Cord in Jury / 대한비뇨기과학회지
Korean Journal of Urology
; : 61-64, 1998.
Article
in Ko
| WPRIM
| ID: wpr-124148
Responsible library:
WPRO
ABSTRACT
PURPOSE: Nocturia and enuresis are common voiding problems in spinal cord injured patients despite a variety of management. The purpose of this study is to determine the efficacy of desmopressin, a synthetic analogue of antidiuretic mono, as an alternative treatment in the management of spinal cord injured(SCI) patients with neurogenic bladder dysfunction unresponsive to conventional therapy. MATERIALS AND METHODS: Fourteen SCI patients with nocturia or enuresis were included in this study. The patients received 10microgram desmopressin intranasally at bedtime once every 24 hours. RESULTS: There was a significant decrease in nocturnal urinary volume, frequency of nocturia and nocturnal enuresis during nighttime after desmopressin administration. Two patients stopped desmopressin because of side effects. 8 of 12 patients improved with desmopressin and the remainder had no effect. There was no serum abnormality, although there were side effects in three cases, such as gastro-intestinal trouble, chest discomfort or nasal congestion. CONCLUSIONS: Desmopressin is safe and effective in the management of nocturia or enuresis due to neurogenic bladder dysfunction in selected SCI patients.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Spinal Cord
/
Spinal Cord Injuries
/
Thorax
/
Urinary Bladder, Neurogenic
/
Estrogens, Conjugated (USP)
/
Deamino Arginine Vasopressin
/
Enuresis
/
Nocturnal Enuresis
/
Nocturia
Limits:
Humans
Language:
Ko
Journal:
Korean Journal of Urology
Year:
1998
Type:
Article