The effect of body mass index of on the outcome of in vitro fertilization and embryo transfer in patients with polycystic ovary syndrome / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology
;
: 75-82, 2009.
Article
in Korean
| WPRIM
| ID: wpr-124408
ABSTRACT
OBJECTIVE:
This study was performed to evaluate the effect of body mass index (BMI) on the outcome of in vitro fertilization and embryo transfer (IVF-ET) in patients with polycystic ovary syndrome (PCOS).METHODS:
Ninety-six patients with PCOS who completed their first cycle of IVF-ET were included in this retrospective study. All patients were stimulated by GnRH antagonist multi-dose protocol. The patients were divided into one of two groups on the basis of BMI > or =23 kg/m2 vs. BMI or =23kg/m2 were divided into patient group with 23 or =25 kg/m2, and these three groups were also compared in regard to the outcome of IVF-ET.RESULTS:
The total amount and duration of rhFSH administration were significantly higher in PCOS women with BMI > or =23 kg/m2 than in those with BMI or =23 kg/m2 (17.4% vs 7.8%, P=0.024). When compared three group divided on the basis of BMI or =25 kg/m2, similar results were showed in women with BMI > or =25 kg/m2, although implantation rate in women with BMI > or =25 kg/m2 was lower with borderline significance (P=0.069).CONCLUSION:
Obesity (BMI > or =23 kg/m2) has a detrimental effect on implantation rate and is associated with the increased total amount and duration of rhFSH administration for ovarian stimulation in IVF-ET cycle. Consequently BMI may be a predictor for IVF outcomes in patients with PCOS.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ovulation Induction
/
Polycystic Ovary Syndrome
/
Fertilization in Vitro
/
Body Mass Index
/
Retrospective Studies
/
Gonadotropin-Releasing Hormone
/
Embryo Transfer
/
Embryonic Structures
/
Obesity
Type of study:
Observational study
/
Prognostic study
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Obstetrics and Gynecology
Year:
2009
Type:
Article
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