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A case of atypical hemolytic uremic syndrome as an early manifestation of acute lymphoblastic leukemia / 소아과
Korean Journal of Pediatrics ; : 253-257, 2010.
Article in English | WPRIM | ID: wpr-125466
ABSTRACT
Hemolytic uremic syndrome (HUS) is the most common cause of acute renal failure in children younger than 4 years and is characterized by microangiopathic hemolytic anemia, acute renal failure, and thrombocytopenia. HUS associated with diarrheal prodrome is usually caused by Shiga toxin-producing Escherichia coli O157H7 or by Shigella dysenteriae, which generally has a better outcome. However, atypical cases show a tendency to relapse with a poorer prognosis. HUS has been reported to be associated with acute lymphoblastic leukemia (ALL) in children. The characteristics and the mechanisms underlying this condition are largely unknown. In this study, we describe the case of an 11-year-old boy in whom the diagnosis of ALL was preceded by the diagnosis of atypical HUS. Thus, patients with atypical HUS should be diagnosed for the possibility of developing ALL.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Prognosis / Recurrence / Shigella dysenteriae / Thrombocytopenia / Shiga-Toxigenic Escherichia coli / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Acute Kidney Injury / Hemolytic-Uremic Syndrome / Anemia, Hemolytic Type of study: Prognostic study Limits: Child / Humans Language: English Journal: Korean Journal of Pediatrics Year: 2010 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Prognosis / Recurrence / Shigella dysenteriae / Thrombocytopenia / Shiga-Toxigenic Escherichia coli / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Acute Kidney Injury / Hemolytic-Uremic Syndrome / Anemia, Hemolytic Type of study: Prognostic study Limits: Child / Humans Language: English Journal: Korean Journal of Pediatrics Year: 2010 Type: Article