The Effect of Single Hemodialysis to Nerve Conduction in Patients with Chronic Renal Insufficiency

ABSTRACT

We studied 16 uremic out-patients in terms of motor nerve conduction velocity (MNCV) and sensory latency, who had ungergone hemodialysis regularly at Maryknoll Hospital, Busan for 5 months, from Dec. 1982 to Apr. 1983. We checked, before and after single hemodialysis, MNCV of median, ulnar, peroneal, and posterior tibial nerves along with sensory lateny of median and ulnar nerves. We got the following as a result. 1. MNCV, before and after hemodialysis, was 47.2 +/- 4.6 m/sec to 50.0+/-2.6 m/sec (p 0.05) in median nerve, 50.0 +/- 4.5 m/sec to 52.4 +/- 3.2 m/sec (p 0.05) in ulnar nerve, 43.0 +/- 5.4 m/sec to 41.1 +/- 4.2 m/sec (statistically not significant) in peroneal nerve, and 41.5 +/- 4.8 m/sec to 43.8 +/-3.9 m/sec (statistically not significant) in posterior tibial nerve. It was pointed out that MNCV in particular of median and ulnar nerves increased. 2. Sensory latency, before and after hemodialysis, was 4.5+/-0.6 m/sec to 3.9+/-0.4 m/sec (p 0.05) in median nerve and 4.7 +/-0.9 m/sec to 4.0 +/- 0.3 m/sec (p 0.01) in ulnar nerve. This showed that sensory latency of median and ulnar nerves decreased significantly. 3. The serum concentration of BUN and creatinine, before and after hemodialysis, was, on an average, 97.8 +/- 18.2 mg/dl (50.7-136.7) to 34.4 +/- 9.5 mg/dl (7.9-20.1 mg/dl) and 14.8 +/- 3.2 mg/dl (7.7-20.1 mg/dl) to 6.2 +/- 1.7 mg/dl (2.4-8.6mg/dl) in each. This showed marked decreased after hemodialysis in serum concentration but meant no correlation with MNCV and sensory latency.