A Study for Assessing the Irritancy of Toilet Soaps and Soap Ingredients / 대한피부과학회지

ABSTRACT

In the present study soap chamber test was carried out for assessing irritancy of toilet soaps and soap ingredients. The results obtained in the present study are summarized as follows; This chamber test can discriminate the differences of irritancies between various soaps and soap ingredients. 2. Soap irritancy is not directly related with its alkalinity. 3, Erythema score and scaling score tend to parallel each other with weak correlation(r=p 46), but erythema score and fissuring score show strong correlation (r=p77) Scaling score and fissuring score show moderate correlation(r=p.64), 4. In the eighteen kinds of toilet soaps, two soaps are most irritating, harsh soap and the total irritancy scores of all soaps are within 1. 9 5. 1. Baby soaps are not milder than the common toilet soaps. 5. Generally, total irritancy score of soap ingredients is concentration dependent. Average total irritancy scores of five main soap ingredients in 4 times of recommended allergen concentration are as follows; Builders 5. 30, Perfumes l. 88, Color 0. 70, Fatty acids p. 35 and Superfat p.