The impact of high-flux dialysis on mortality rates in incident and prevalent hemodialysis patients
The Korean Journal of Internal Medicine
;
: 774-784, 2014.
Article
in English
| WPRIM
| ID: wpr-126098
ABSTRACT
BACKGROUND/AIMS:
The effect of high-flux (HF) dialysis on mortality rates could vary with the duration of dialysis. We evaluated the effects of HF dialysis on mortality rates in incident and prevalent hemodialysis (HD) patients.METHODS:
Incident and prevalent HD patients were selected from the Clinical Research Center registry for end-stage renal disease (ESRD), a Korean prospective observational cohort study. Incident HD patients were defined as newly diagnosed ESRD patients initiating HD. Prevalent HD patients were defined as patients who had been receiving HD for > 3 months. The primary outcome measure was all-cause mortality.RESULTS:
This study included 1,165 incident and 1,641 prevalent HD patients. Following a median 24 months of follow-up, the mortality rates of the HF and low-flux (LF) groups did not significantly differ in the incident patients (hazard ratio [HR], 1.046; 95% confidence interval [CI], 0.592 to 1.847; p = 0.878). In the prevalent patients, HF dialysis was associated with decreased mortality compared with LF dialysis (HR, 0.606; 95% CI, 0.416 to 0.885; p = 0.009).CONCLUSIONS:
HF dialysis was associated with a decreased mortality rate in prevalent HD patients, but not in incident HD patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Time Factors
/
Chi-Square Distribution
/
Proportional Hazards Models
/
Registries
/
Incidence
/
Prevalence
/
Multivariate Analysis
/
Prospective Studies
/
Risk Factors
/
Renal Dialysis
Type of study:
Etiology study
/
Incidence study
/
Observational study
/
Prevalence study
/
Prognostic study
/
Risk factors
Limits:
Aged
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
The Korean Journal of Internal Medicine
Year:
2014
Type:
Article
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