Cytomegalovirus Esophagitis in Renal Transplant Recipient / 대한이식학회지

ABSTRACT

Cytomegalovirus (CMV) infection of the gastrointestinal tract can cause serious disease in immunocompromised patients. Recipients of solid organ and bone marrow transplants, persons with malignancies, persons with immune deficiency due to acquired immune deficiency syndrome (AIDS), and those receiving immunosuppressive medication are at risk. When CMV infection of the GI tract causes disease, symptoms include pain, ulceration, bleeding, diarrhea, and perforation. All level of GI tract, from the oropharynx to anus, may be involved. The CMV has been associated with gastric and enteric ulcerations, but infrequently with esophageal infection. Two cases of CMV induced esophagitis have been reported in Korea. We report one recipient of kidney transplant who had esophageal ulceration associated with CMV infection which showed characteristic endoscopic and histologic finding of CMV esophagitis.