DNA Pooling as a Tool for Case-Control Association Studies of Complex Traits
Genomics & Informatics
;
: 1-7, 2005.
Article
in English
| WPRIM
| ID: wpr-126999
ABSTRACT
Case-control studies are widely used for disease gene mapping using individual genotyping data. However, analyses of large samples are often impractical due to the expense of individual genotyping. The use of DNA pooling can significantly reduce the number of genotyping reactions required; hence reducing the cost of large-scale case-control association studies. Here, we discuss the design and analysis of DNA pooling genetic association studies.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
DNA
/
Case-Control Studies
/
Chromosome Mapping
/
Genetic Association Studies
Type of study:
Observational study
/
Risk factors
Language:
English
Journal:
Genomics & Informatics
Year:
2005
Type:
Article
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