F18-fluorodeoxyglucose-positron emission tomography and computed tomography is not accurate in preoperative staging of gastric cancer / 대한외과학회지
Journal of the Korean Surgical Society
;
: 104-110, 2011.
Article
in English
| WPRIM
| ID: wpr-127568
ABSTRACT
PURPOSE:
To investigate the clinical benefits of F18-fluorodeoxyglucose-positron emission tomography and computed tomography (18F-FDG-PET/CT) over multi-detector row CT (MDCT) in preoperative staging of gastric cancer.METHODS:
FDG-PET/CT and MDCT were performed on 78 patients with gastric cancer pathologically diagnosed by endoscopy. The accuracy of radiologic staging retrospectively was compared to pathologic result after curative resection.RESULTS:
Primary tumors were detected in 51 (65.4%) patients with 18F-FDG-PET/CT, and 47 (60.3%) patients with MDCT. Regarding detection of lymph node metastasis, the sensitivity of FDG-PET/CT was 51.5% with an accuracy of 71.8%, whereas those of MDCT were 69.7% and 69.2%, respectively. The sensitivity of 18F-FDG-PET/CT for a primary tumor with signet ring cell carcinoma was lower than that of 18F-FDG-PET/CT for a primary tumor with non-signet ring cell carcinoma (35.3% vs. 73.8%, P < 0.01).CONCLUSION:
Due to its low sensitivity, 18F-FDG-PET/CT alone shows no definite clinical benefit for prediction of lymph node metastasis in preoperative staging of gastric cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Stomach Neoplasms
/
Retrospective Studies
/
Carcinoma, Signet Ring Cell
/
Endoscopy
/
Lymph Nodes
/
Neoplasm Metastasis
Type of study:
Observational study
Limits:
Humans
Language:
English
Journal:
Journal of the Korean Surgical Society
Year:
2011
Type:
Article
Similar
MEDLINE
...
LILACS
LIS